Dietary lycopene attenuates cigarette smoke-promoted nonalcoholic steatohepatitis by preventing suppression of antioxidant enzymes in ferrets

Cigarette smoke (CS) is an independent risk factor in development of nonalcoholic steatohepatitis (NASH) and fibrosis. Lycopene, a carotenoid naturally occurring in tomatoes, has been shown to be a protective agent against tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induc...

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Veröffentlicht in:	The Journal of nutritional biochemistry 2021-05, Vol.91, p.108596-108596, Article 108596
Hauptverfasser:	Mustra Rakic, Jelena, Liu, Chun, Veeramachaneni, Sudipta, Wu, Dayong, Paul, Ligi, Ausman, Lynne M., Wang, Xiang-Dong
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - therapeutic use BCO2 Cigarette smoke Cigarette Smoking - adverse effects Dietary Supplements Ferrets Lycopene Lycopene - therapeutic use Male NASH Non-alcoholic Fatty Liver Disease - enzymology Non-alcoholic Fatty Liver Disease - etiology Non-alcoholic Fatty Liver Disease - therapy Oxidative Stress Preclinical prevention
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