Efficient synthesis of spirooxindolyl oxazol-2(5 H )-ones via palladium(ii)-catalyzed addition of arylboronic acids to nitriles
A versatile synthesis of spirooxindolyl oxazol-2(5 )-ones palladium(ii)-catalyzed addition of arylboronic acids to nitriles is described. A wide range of spirooxindolyl oxazol-2(5 )-ones and other spirocyclic frameworks incorporating the oxazol-2(5 )-one unit can be readily prepared in good to high...
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Veröffentlicht in: | RSC advances 2019-09, Vol.9 (50), p.29424-29428 |
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Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
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Online-Zugang: | Volltext |
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Zusammenfassung: | A versatile synthesis of spirooxindolyl oxazol-2(5
)-ones
palladium(ii)-catalyzed addition of arylboronic acids to nitriles is described. A wide range of spirooxindolyl oxazol-2(5
)-ones and other spirocyclic frameworks incorporating the oxazol-2(5
)-one unit can be readily prepared in good to high yields under the optimal conditions. |
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ISSN: | 2046-2069 2046-2069 |
DOI: | 10.1039/c9ra07216k |