Molecular docking analysis of penta galloyl glucose with the bcl-2 family of anti-apoptotic targets

Apoptosis requires cellular proteins from the B-cell lymphoma 2 (BCL-2) family linked to breast cancer. Therefore, it is of interest to document the Molecular docking analysis data of penta galloyl glucose with the bcl-2 family of anti-apoptotic targets (Bcl-2, BCL-XL, Caspase 3, and Caspase 9). Dat...

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Veröffentlicht in:Bioinformation 2021-10, Vol.17 (10), p.861-865
Hauptverfasser: Dharmalingam, Karthick, Dharmalingam, Velvizhi, Durairaj, Satheesh, Sharma, Praveen, Jayaraman, Selvaraj, Choudhary, Sarita
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Sprache:eng
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Zusammenfassung:Apoptosis requires cellular proteins from the B-cell lymphoma 2 (BCL-2) family linked to breast cancer. Therefore, it is of interest to document the Molecular docking analysis data of penta galloyl glucose with the bcl-2 family of anti-apoptotic targets (Bcl-2, BCL-XL, Caspase 3, and Caspase 9). Data shows that Pentagalloyl glucose have optimal binding features with Bcl-2, BCL-XL, Caspase 3, and Caspase 9 proteins with binding energy of -8.6,-7,-7.5 and 4.4 kcal/mol respectively for further consideration in this context.
ISSN:0973-2063
0973-8894
0973-2063
DOI:10.6026/97320630017861