Respiratory Care Innovation in Times of Crisis

System-based modifications such as resistors, clamps, and valves have enabled varying levels of control in carefully matched patients.10,11 In addition, the ability to monitor, overcome ventilator self-tests, exposure, and alarms have been overcome by recent systems.11 Splitting high flow oxygen delivered by a mask or a nasal cannula is certainly less risky, although the rate of oxygen consumption would be increased without special valving leading to accelerated depletion of oxygen reservoirs. In 2021, insufficient oxygen reserves and widespread use for COVID-19 patients created drastic shortages, leading to increased mortality in India.12 Technologies to cost-effectively expand high-flow nasal oxygen systems without wastage would benefit health care infrastructures experiencing high caseloads.—Shriya S. Srinivasan, PhD, Department of Mechanical Engineering, Massachusetts Institute of Technology, Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women’s Hospital, Harvard Medical School, David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Project Prana Foundation, Cambridge 02139, Boston 02115, MA, United States; E-mail: shriyas@mit.edu. Twitter: rajibmndl; Khalil B. Ramadi, PhD, Department of Mechanical Engineering and David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology; Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital, Harvard Medical School; Project Prana Foundation, Cambridge 02139, MA, United States.