In vitro growth of Leishmania amazonensis promastigotes resistant to pentamidine is dependent on interactions among strains

The in vitro growth of promastigote cells of Leishmania amazonensis was found to strongly depend on interactions among strains that differed in their pentamidine resistance. In particular, the growth of resistant strains was reduced when they shared the same environment with a less-resistant strain.

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Bibliographische Detailangaben
Veröffentlicht in:	Antimicrobial agents and chemotherapy 2001-06, Vol.45 (6), p.1928-1929
Hauptverfasser:	AGNEW, P, HOLZMULLER, P, MICHALAKIS, Y, SERENO, D, LEMESRE, J. L, RENAUD, F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Antiparasitic agents Antiprotozoal Agents - pharmacology Bacteriology Biological and medical sciences Drug Resistance, Microbial Fundamental and applied biological sciences. Psychology Genetics Leishmania - drug effects Leishmania - growth & development Medical sciences Microbiology Pentamidine - pharmacology Pharmacology. Drug treatments Species Specificity Susceptibility
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Beschreibung
Zusammenfassung:	The in vitro growth of promastigote cells of Leishmania amazonensis was found to strongly depend on interactions among strains that differed in their pentamidine resistance. In particular, the growth of resistant strains was reduced when they shared the same environment with a less-resistant strain.
ISSN:	0066-4804 1098-6596
DOI:	10.1128/AAC.45.6.1928-1929.2001