Safety and efficacy of graded dosing of Pfizer-BioNTech mRNA COVID-19 vaccine after an immediate hypersensitivity reaction to first dose

Current guidelines do not recommend subsequent mRNA COVID-19 vaccination in patients who experience immediate allergic reactions to the first dose. Our findings indicate that graded dosing of this vaccine is safe, efficacious, and useful for treating these individuals with allergy.

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Bibliographische Detailangaben
Veröffentlicht in:	The journal of allergy and clinical immunology. Global 2022-08, Vol.1 (3), p.175-177
Hauptverfasser:	Regula, Prudhvi, Rosenstreich, David, Jerschow, Elina, Ramesh, Manish, Ferastraoaru, Denisa, Oh, Jessica, Aivazi, Daniella S., Aivazi, Jonathan M., Hudes, Golda
Format:	Artikel
Sprache:	eng
Schlagworte:	Case Report COVID-19 vaccines Graded dosing of vaccine mRNA vaccine allergy vaccine desensitization vaccine hesitancy
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Current guidelines do not recommend subsequent mRNA COVID-19 vaccination in patients who experience immediate allergic reactions to the first dose. Our findings indicate that graded dosing of this vaccine is safe, efficacious, and useful for treating these individuals with allergy.
ISSN:	2772-8293 2772-8293
DOI:	10.1016/j.jacig.2022.04.005