Bacteriophage therapy

In this minireview, we briefly describe the history of bacteriophage discovery and the early clinical studies with phages and we review the recent literature emphasizing research conducted in Poland and the former Soviet Union. We also discuss the reasons that the clinical use of bacteriophages fail...

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Veröffentlicht in:	Antimicrobial agents and chemotherapy 2001-03, Vol.45 (3), p.649-659
Hauptverfasser:	SULAKVELIDZE, Alexander, ALAVIDZE, Zemphira, MORRIS, J. Glenn
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Bacterial Agents - therapeutic use Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Bacillus subtilis Bacterial Infections Bacterial Infections - drug therapy Bacterial Infections - therapy Bacteriophages Bacteriophages - growth & development Bacteriophages - physiology Biological and medical sciences Biological Therapy Disease Models, Animal Humans Medical sciences Minireview Minireviews Pharmacology. Drug treatments Shigella Vibrio cholerae
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Beschreibung
Zusammenfassung:	In this minireview, we briefly describe the history of bacteriophage discovery and the early clinical studies with phages and we review the recent literature emphasizing research conducted in Poland and the former Soviet Union. We also discuss the reasons that the clinical use of bacteriophages failed to take root in the West, and we share our thoughts about future prospects for phage therapy research.
ISSN:	0066-4804 1098-6596
DOI:	10.1128/AAC.45.3.649-659.2001