The Importance of the Tumor Microenvironment to Understand Tumor Origin, Evolution, and Treatment Response

The Importance of the Tumor Microenvironment to Understand Tumor Origin, Evolution, and Treatment Response

During the second half of the twentieth century, oncology adopted a tumor-centric approach to cancer treatment, focusing primarily on the tumor cell to identify new therapeutic targets [...].

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Bibliographische Detailangaben
Veröffentlicht in:Cancers 2022-04, Vol.14 (8), p.1983
Hauptverfasser: Ayuso, Jose M, Ochoa Garrido, Ignacio
Format: Artikel
Sprache:eng
Schlagworte:
Bone marrow
Brain cancer
Breast cancer
Cancer therapies
Cell activation
Cell growth
Epidermal growth factor
Evolution
Fibroblasts
Gap junctions
Gene expression
Glutathione
Hypoxia
Interleukin 6
Interleukin 8
Kinases
Mathematical models
Medical prognosis
Medical research
Melanoma
Metastases
Metastasis
Microglia
Mutation
Osteoblasts
Oxidative stress
Platelet-derived growth factor
Proteins
Radiation therapy
Senescence
Tumor cells
Tumor microenvironment
Tumors
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Zusammenfassung:During the second half of the twentieth century, oncology adopted a tumor-centric approach to cancer treatment, focusing primarily on the tumor cell to identify new therapeutic targets [...].
ISSN:2072-6694
2072-6694
DOI:10.3390/cancers14081983