Clinical Features of Parosmia Associated With COVID‐19 Infection

Objective To characterize the clinical features, risk factors, symptom time‐course, and quality of life implications for parosmia among coronavirus disease (COVID)‐related olfactory dysfunction patients. Methods Individuals with olfactory dysfunction associated with laboratory‐confirmed or clinicall...

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Veröffentlicht in:The Laryngoscope 2022-03, Vol.132 (3), p.633-639
Hauptverfasser: Lerner, David K., Garvey, Katherine L., Arrighi‐Allisan, Annie E., Filimonov, Andrey, Filip, Peter, Shah, Janki, Tweel, Benjamin, Del Signore, Anthony, Schaberg, Madeleine, Colley, Patrick, Govindaraj, Satish, Iloreta, Alfred Marc
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Sprache:eng
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Zusammenfassung:Objective To characterize the clinical features, risk factors, symptom time‐course, and quality of life implications for parosmia among coronavirus disease (COVID)‐related olfactory dysfunction patients. Methods Individuals with olfactory dysfunction associated with laboratory‐confirmed or clinically suspected COVID‐19 infection were recruited from otolaryngology and primary care practices over a period from August 2020 to March 2021. Participants completed olfactory dysfunction and quality of life surveys. Results A total of 148 (64.1%) of 231 respondents reported parosmia at some point. Parosmia developed within 1 week of any COVID‐19 symptom onset in 25.4% of respondents, but more than 1 month after symptom onset in 43.4% of respondents. Parosmia was associated with significantly better quantitative olfactory scores on Brief Smell Identification Test (8.7 vs. 7.5, P = .006), but demonstrated worse quality of life scores, including modified brief Questionnaire of Olfactory Dysfunction—Negative Statements and Sino‐Nasal Outcome Test‐22 scores (12.1 vs. 8.5, P 
ISSN:0023-852X
1531-4995
DOI:10.1002/lary.29982