BNT162b2 Third Booster Dose Significantly Increases the Humoral Response Assessed by Both RBD IgG and Neutralizing Antibodies in Renal Transplant Recipients

BNT162b2 Third Booster Dose Significantly Increases the Humoral Response Assessed by Both RBD IgG and Neutralizing Antibodies in Renal Transplant Recipients

An impaired humoral response to full dose of BNT162b2 vaccine was observed in renal transplant recipients (RTR). To reveal predictors for humoral response to third vaccine, patients were stratified to positive (N = 85) and negative (N = 14) response groups based on receptor-binding domain (RBD) IgG...

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Veröffentlicht in:Transplant international 2022-03, Vol.35, p.10239-10239
Hauptverfasser: Hod, Tammy, Ben-David, Aharon, Olmer, Liraz, Scott, Noa, Ghinea, Ronen, Mor, Eytan, Levy, Itzchak, Indenbaum, Victoria, Lustig, Yaniv, Grossman, Ehud, Rahav, Galia
Format: Artikel
Sprache:eng
Schlagworte:
Antibodies, Neutralizing
Antibodies, Viral
BNT162 Vaccine
COVID-19
COVID-19 Vaccines
Health Archive
Humans
Immunoglobulin G
Kidney Transplantation
Mycophenolic Acid
SARS-CoV-2
Transplant Recipients
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Zusammenfassung:An impaired humoral response to full dose of BNT162b2 vaccine was observed in renal transplant recipients (RTR). To reveal predictors for humoral response to third vaccine, patients were stratified to positive (N = 85) and negative (N = 14) response groups based on receptor-binding domain (RBD) IgG ≥1.1 and neutralizing antibodies (NA) ≥ 16 dilution versus RBD IgG
ISSN:1432-2277
0934-0874
1432-2277
DOI:10.3389/ti.2022.10239