Human Vitreous Collagen Fragments Dimension As a Function of Vitrectomy Cut Rate

Human Vitreous Collagen Fragments Dimension As a Function of Vitrectomy Cut Rate

To study the dimensions and distribution of human vitreous collagen type II fragments collected after vitrectomy performed at varying cut rates and to evaluate if increasing the cut rate produces smaller collagen fragments, thus reducing retinal traction and/or viscosity. Fluid was collected during...

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Veröffentlicht in:Translational vision science & technology 2022-03, Vol.11 (3), p.29-29
Hauptverfasser: Rossi, Tommaso, Speciale, Andrea, Menichini, Paola, Izzotti, Alberto, D'Agostino, Isabella, Trillo, Carlandrea, Telani, Serena, Querzoli, Giorgio, Ripandelli, Guido
Format: Artikel
Sprache:eng
Schlagworte:
Collagen - metabolism
Collagen Type II - metabolism
Humans
Viscosity
Vitrectomy - methods
Vitreous Body - metabolism
Vitreous Body - surgery
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Zusammenfassung:To study the dimensions and distribution of human vitreous collagen type II fragments collected after vitrectomy performed at varying cut rates and to evaluate if increasing the cut rate produces smaller collagen fragments, thus reducing retinal traction and/or viscosity. Fluid was collected during core vitrectomies performed for macular surgery at cut rates from 1000 to 16,000 cuts per minute (CPM) and immediately refrigerated. Protein fractions were separated by molecular weight (MW; >100 kDa, 50-100 kDa, 50-30 kDa, 30-10 kDa, and
ISSN:2164-2591
2164-2591
DOI:10.1167/tvst.11.3.29