Fluidity is the way to life: lipid phase separation in bacterial membranes
A hallmark of biological membranes is the dynamic localization of lipids and proteins. Lipids respond to temperature reduction below a critical point with phase separation, and poikilothermic animals and also bacteria adapt their lipid content to prevent gel phase formation in membranes. In a new st...
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| Veröffentlicht in: | The EMBO journal 2022-03, Vol.41 (5), p.e110737-n/a |
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| creator | Bramkamp, Marc |
| description | A hallmark of biological membranes is the dynamic localization of lipids and proteins. Lipids respond to temperature reduction below a critical point with phase separation, and poikilothermic animals and also bacteria adapt their lipid content to prevent gel phase formation in membranes. In a new study, Gohrbandt
et al
(2022) show that reduced membrane fluidity in bacterial cells causes reversible phase separation without membrane rupture
in vivo
, highlighting the physical robustness of biological membranes.
Graphical Abstract
A new study provides a first example of a co‐existing gel/fluid phase separation in a bacterial cell. |
| doi_str_mv | 10.15252/embj.2022110737 |
| format | Article |
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et al
(2022) show that reduced membrane fluidity in bacterial cells causes reversible phase separation without membrane rupture
in vivo
, highlighting the physical robustness of biological membranes.
Graphical Abstract
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et al
(2022) show that reduced membrane fluidity in bacterial cells causes reversible phase separation without membrane rupture
in vivo
, highlighting the physical robustness of biological membranes.
Graphical Abstract
A new study provides a first example of a co‐existing gel/fluid phase separation in a bacterial cell.</description><subject>Animals</subject><subject>Bacteria</subject><subject>Biological membranes</subject><subject>Cell Membrane - metabolism</subject><subject>Critical point</subject><subject>EMBO20</subject><subject>EMBO23</subject><subject>Fluidity</subject><subject>Lipids</subject><subject>Localization</subject><subject>Membrane Fluidity</subject><subject>Membranes</subject><subject>News & Views</subject><subject>Phase separation</subject><subject>Views</subject><subject>Viscosity</subject><issn>0261-4189</issn><issn>1460-2075</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkc1rFTEUxYMo9vl070oCbtxMe5NMJomIoKW1loobXYfMzE1fHvNlMmN5_73RV1tbKG5yF_mdwzkcQl4yOGSSS36Efb095MA5Y6CEekRWrKyg4KDkY7ICXrGiZNockGcpbQFAasWekgMhWSmgVCtyftotoQ3zjoZE5w3SK7ej80i74PFtfqfQ0mnjEtKEk4tuDuNAw0Br18wYg-tonzNEN2B6Tp541yV8cX3X5Pvpybfjs-Li66fPxx8uikYyowqtha-EEYIZyZ3m3htfS9C1k64Bx5yulQNUSvCSGeZAeO4bqLlGbJVoxZq83_tOS91j2-AwR9fZKYbexZ0dXbB3f4awsZfjT6u1rqSQ2eDNtUEcfyyYZtuH1GDX5RbjkiyvuCqVBGMy-voeuh2XOOR6mRKlkIbnoGsCe6qJY0oR_U0YBvbPUPb3UPZ2qCx59W-JG8HfZTLwbg9chQ53_zW0J18-nt_xZ3t5ysrhEuNt8Acz_QLoxK_6</recordid><startdate>20220301</startdate><enddate>20220301</enddate><creator>Bramkamp, Marc</creator><general>Nature Publishing Group UK</general><general>Blackwell Publishing Ltd</general><general>John Wiley and Sons Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QG</scope><scope>7QL</scope><scope>7QP</scope><scope>7T5</scope><scope>7TK</scope><scope>7TM</scope><scope>7TO</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>K9.</scope><scope>M7N</scope><scope>P64</scope><scope>RC3</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-7704-3266</orcidid></search><sort><creationdate>20220301</creationdate><title>Fluidity is the way to life: lipid phase separation in bacterial membranes</title><author>Bramkamp, Marc</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5197-883f639331952a82ff9fb508ba5ac0a1a8b7a0e77324191a03f2fc0b28eed73d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Animals</topic><topic>Bacteria</topic><topic>Biological membranes</topic><topic>Cell Membrane - 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et al
(2022) show that reduced membrane fluidity in bacterial cells causes reversible phase separation without membrane rupture
in vivo
, highlighting the physical robustness of biological membranes.
Graphical Abstract
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| language | eng |
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| source | Springer Nature OA Free Journals |
| subjects | Animals Bacteria Biological membranes Cell Membrane - metabolism Critical point EMBO20 EMBO23 Fluidity Lipids Localization Membrane Fluidity Membranes News & Views Phase separation Views Viscosity |
| title | Fluidity is the way to life: lipid phase separation in bacterial membranes |
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