Cytomegalovirus Infection Is Associated With Increased Prevalence of Latent Tuberculosis Infection

Cytomegalovirus Infection Is Associated With Increased Prevalence of Latent Tuberculosis Infection

Abstract Cytomegalovirus (CMV) increases tuberculosis (TB) risk, but its relationship with latent TB infection (LTBI) is unknown. Using US nationally representative data, we report that CMV was independently associated with LTBI (odds ratio, 2.94; 95% CI, 1.19–7.28; P=.02). CMV and LTBI were associa...

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Veröffentlicht in:Open Forum Infectious Diseases 2021-11, Vol.8 (11), p.ofab539-ofab539
Hauptverfasser: van der Heijden, Yuri F, Zhang, Bin, Chougnet, Claire A, Huaman, Moises A
Format: Artikel
Sprache:eng
Schlagworte:
BCG
BCG vaccines
Brief Reports
C-reactive protein
Cytomegalovirus infections
Development and progression
Diseases
Epidemiology
Health aspects
HIV (Viruses)
Ohio
Tuberculosis
Virus diseases
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Zusammenfassung:Abstract Cytomegalovirus (CMV) increases tuberculosis (TB) risk, but its relationship with latent TB infection (LTBI) is unknown. Using US nationally representative data, we report that CMV was independently associated with LTBI (odds ratio, 2.94; 95% CI, 1.19–7.28; P=.02). CMV and LTBI were associated with higher C-reactive protein, suggesting chronic inflammation.
ISSN:2328-8957
2328-8957
DOI:10.1093/ofid/ofab539