Long-Term Mortality and State Financial Support in Invasive Meningococcal Disease—Real-World Data Analysis Using the French National Claims Database (SNIIRAM)

Objectives Invasive meningococcal disease (IMD) is an uncommon disease known for its acute phase mortality and long-term sequelae. The objective was to assess the impact of IMD on post-discharge mortality risk and dependence on the French state for financial aid. Methods A 6-year retrospective analysis in the national insurance database (SNIIRAM) assessed mortality in IMD cases (both during acute phase and post-discharge) and matched controls as well as benefit claims (i.e., for salary loss compensation [SLC], long-term sickness [ALD] and complementary health insurance [CMUc]). Observed survival data were extrapolated to estimate lifetime life expectancy following IMD. Results Between 2012 and 2017, 3532 incident IMD cases were hospitalised in France (peak in