RCandy: an R package for visualizing homologous recombinations in bacterial genomes

Abstract Summary Homologous recombination is an important evolutionary process in bacteria and other prokaryotes, which increases genomic sequence diversity and can facilitate adaptation. Several methods and tools have been developed to detect genomic regions recently affected by recombination. Expl...

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Veröffentlicht in:Bioinformatics (Oxford, England) England), 2022-02, Vol.38 (5), p.1450-1451
Hauptverfasser: Chaguza, Chrispin, Tonkin-Hill, Gerry, Lo, Stephanie W, Hadfield, James, Croucher, Nicholas J, Harris, Simon R, Bentley, Stephen D
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Sprache:eng
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Zusammenfassung:Abstract Summary Homologous recombination is an important evolutionary process in bacteria and other prokaryotes, which increases genomic sequence diversity and can facilitate adaptation. Several methods and tools have been developed to detect genomic regions recently affected by recombination. Exploration and visualization of such recombination events can reveal valuable biological insights, but it remains challenging. Here, we present RCandy, a platform-independent R package for rapid, simple and flexible visualization of recombination events in bacterial genomes. Availability and implementation RCandy is an R package freely available for use under the MIT license. It is platform-independent and has been tested on Windows, Linux and MacOSX. The source code comes together with a detailed vignette available on GitHub at https://github.com/ChrispinChaguza/RCandy. Supplementary information Supplementary data are available at Bioinformatics online.
ISSN:1367-4803
1367-4811
DOI:10.1093/bioinformatics/btab814