A Causal Link Between Disrupted AKT Signaling and Hyperproliferative Endometrial Diseases

A Causal Link Between Disrupted AKT Signaling and Hyperproliferative Endometrial Diseases

Abbreviations: DES, diethylstilbestrol; E2, estradiol; ESR, estrogen receptor; mESR, membrane-bound estrogen receptor; NOER, nuclear-only (lacking membrane) ER[alpha]; P4, progesterone; PGR, progesterone receptor; PI3K, phosphatidylinositol 3-kinase; PIP3, phosphatidylinositol-3,4,5-trisphosphate; p...

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Veröffentlicht in:Endocrinology (Philadelphia) 2022-03, Vol.163 (3), p.1
1. Verfasser: Pru, James K
Format: Artikel
Sprache:eng
Schlagworte:
AKT protein
Endocrinology
Endometrial cancer
Endometrium
Estradiol
Humans
Phosphatases
Progesterone
Proto-Oncogene Proteins c-akt - genetics
Proto-Oncogene Proteins c-akt - metabolism
Signal Transduction
Uterine Diseases
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description Abbreviations: DES, diethylstilbestrol; E2, estradiol; ESR, estrogen receptor; mESR, membrane-bound estrogen receptor; NOER, nuclear-only (lacking membrane) ER[alpha]; P4, progesterone; PGR, progesterone receptor; PI3K, phosphatidylinositol 3-kinase; PIP3, phosphatidylinositol-3,4,5-trisphosphate; pnd, postnatal day; PTEN, phosphatase and tensin homolog.
doi_str_mv 10.1210/endocr/bqac006
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subjects AKT protein
Endocrinology
Endometrial cancer
Endometrium
Estradiol
Humans
Phosphatases
Progesterone
Proto-Oncogene Proteins c-akt - genetics
Proto-Oncogene Proteins c-akt - metabolism
Signal Transduction
Uterine Diseases
title A Causal Link Between Disrupted AKT Signaling and Hyperproliferative Endometrial Diseases
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