A Causal Link Between Disrupted AKT Signaling and Hyperproliferative Endometrial Diseases

Abbreviations: DES, diethylstilbestrol; E2, estradiol; ESR, estrogen receptor; mESR, membrane-bound estrogen receptor; NOER, nuclear-only (lacking membrane) ER[alpha]; P4, progesterone; PGR, progesterone receptor; PI3K, phosphatidylinositol 3-kinase; PIP3, phosphatidylinositol-3,4,5-trisphosphate; p...

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Veröffentlicht in:	Endocrinology (Philadelphia) 2022-03, Vol.163 (3), p.1
1. Verfasser:	Pru, James K
Format:	Artikel
Sprache:	eng
Schlagworte:	AKT protein Endocrinology Endometrial cancer Endometrium Estradiol Humans Phosphatases Progesterone Proto-Oncogene Proteins c-akt - genetics Proto-Oncogene Proteins c-akt - metabolism Signal Transduction Uterine Diseases
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Abbreviations: DES, diethylstilbestrol; E2, estradiol; ESR, estrogen receptor; mESR, membrane-bound estrogen receptor; NOER, nuclear-only (lacking membrane) ER[alpha]; P4, progesterone; PGR, progesterone receptor; PI3K, phosphatidylinositol 3-kinase; PIP3, phosphatidylinositol-3,4,5-trisphosphate; pnd, postnatal day; PTEN, phosphatase and tensin homolog.
ISSN:	0013-7227 1945-7170
DOI:	10.1210/endocr/bqac006