Effectiveness of Covid-19 Vaccines over a 9-Month Period in North Carolina

In an analysis involving more than 10 million North Carolina residents, Covid-19 vaccines were highly effective in preventing hospitalization and death up to 9 months after vaccination. Waning protection against infection over time was due to both declining immunity and the emergence of the delta va...

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Veröffentlicht in:	The New England journal of medicine 2022-03, Vol.386 (10), p.933-941
Hauptverfasser:	Lin, Dan-Yu, Gu, Yu, Wheeler, Bradford, Young, Hayley, Holloway, Shannon, Sunny, Shadia-Khan, Moore, Zack, Zeng, Donglin
Format:	Artikel
Sprache:	eng
Schlagworte:	2019-nCoV Vaccine mRNA-1273 Ad26COVS1 Adolescent Adult Aged BNT162 Vaccine Census of Population Child Clinical outcomes Confidence intervals Coronavirus Coronaviruses COVID-19 - immunology COVID-19 - mortality COVID-19 - prevention & control COVID-19 vaccines Death Disease transmission Estimates Female Health surveillance Hospitalization Hospitalization - statistics & numerical data Humans Immunogenicity, Vaccine Infectious Disease Laboratories Male Middle Aged Minority & ethnic groups mRNA North Carolina - epidemiology Original Pacific Islander people Pandemics SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 Vaccine efficacy Vaccine Efficacy - statistics & numerical data Vaccines Young Adult
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Beschreibung
Zusammenfassung:	In an analysis involving more than 10 million North Carolina residents, Covid-19 vaccines were highly effective in preventing hospitalization and death up to 9 months after vaccination. Waning protection against infection over time was due to both declining immunity and the emergence of the delta variant.
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJMoa2117128