Association between Intermittent Hypoxemia and Severe Bronchopulmonary Dysplasia in Preterm Infants

Association between Intermittent Hypoxemia and Severe Bronchopulmonary Dysplasia in Preterm Infants

Bronchopulmonary dysplasia increases the risk of disability in extremely preterm infants. Although the pathophysiology remains uncertain, prior exposure to intermittent hypoxemia may play a role in this relationship. To determine the association between prolonged episodes of intermittent hypoxemia a...

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Veröffentlicht in:American journal of respiratory and critical care medicine 2021-11, Vol.204 (10), p.1192-1199
Hauptverfasser: Jensen, Erik A, Whyte, Robin K, Schmidt, Barbara, Bassler, Dirk, Vain, Nestor E, Roberts, Robin S
Format: Artikel
Sprache:eng
Schlagworte:
Bronchopulmonary Dysplasia - diagnosis
Bronchopulmonary Dysplasia - etiology
Bronchopulmonary Dysplasia - physiopathology
Bronchopulmonary Dysplasia - therapy
Canada
Clinical trials
Female
Humans
Hypoxia - complications
Hypoxia - therapy
Infant, Extremely Premature
Infant, Newborn
Lung diseases
Male
Original
Premature babies
Pulse oximetry
Respiratory Distress Syndrome, Newborn - complications
Respiratory Distress Syndrome, Newborn - therapy
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Zusammenfassung:Bronchopulmonary dysplasia increases the risk of disability in extremely preterm infants. Although the pathophysiology remains uncertain, prior exposure to intermittent hypoxemia may play a role in this relationship. To determine the association between prolonged episodes of intermittent hypoxemia and severe bronchopulmonary dysplasia. A analysis of extremely preterm infants in the Canadian Oxygen Trial who survived to 36 weeks' postmenstrual age was performed. Oxygen saturations
ISSN:1073-449X
1535-4970
DOI:10.1164/rccm.202105-1150OC