Effect of soy and milk protein supplementation on serum lipid levels: a randomized controlled trial

Background/Objective: Previous clinical trials have documented that soy protein reduces low-density lipoprotein cholesterol and increases high-density lipoprotein (HDL) cholesterol compared with milk protein. However, the effect of soy protein on lipids compared with carbohydrate has not been not we...

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Veröffentlicht in:	European journal of clinical nutrition 2012-04, Vol.66 (4), p.419-425
Hauptverfasser:	Wofford, M R, Rebholz, C M, Reynolds, K, Chen, J, Chen, C-S, Myers, L, Xu, J, Jones, D W, Whelton, P K, He, J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adults Biological and medical sciences Blood Blood lipids Blood pressure Carbohydrates Cardiovascular disease Cholesterol Cholesterol, HDL - blood Cholesterol, HDL - drug effects Cholesterol, LDL - blood Cholesterol, LDL - drug effects Clinical Nutrition Clinical trials Confidence intervals Cross-Over Studies Density Dietary Carbohydrates - administration & dosage Dietary Supplements Double-Blind Method Epidemiology Feeding. Feeding behavior Female Fundamental and applied biological sciences. Psychology Health aspects High density lipoprotein Humans Hypercholesterolemia Hypercholesterolemia - drug therapy Internal Medicine Intervention Lipids Lipoproteins Low density lipoprotein Male Medical sciences Medicine Medicine & Public Health Metabolic Diseases Middle Aged Milk Milk proteins Milk Proteins - administration & dosage original-article Physiological aspects Proteins Public Health Serum Soy protein Soybean products Soybean Proteins - administration & dosage Supplements Triglycerides Triglycerides - blood Vertebrates: anatomy and physiology, studies on body, several organs or systems Wheat
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Zusammenfassung:	Background/Objective: Previous clinical trials have documented that soy protein reduces low-density lipoprotein cholesterol and increases high-density lipoprotein (HDL) cholesterol compared with milk protein. However, the effect of soy protein on lipids compared with carbohydrate has not been not well studied. We examined the effect of soy and milk protein supplementation on lipids and lipoproteins compared with carbohydrate among adults without hypercholesterolemia. Subjects/Methods: We conducted a randomized, double-blind, 3-phase crossover trial among 352 US adults with serum total cholesterol level of
ISSN:	0954-3007 1476-5640
DOI:	10.1038/ejcn.2011.168