Single-molecule sequencing reveals a large population of long cell-free DNA molecules in maternal plasma

In the field of circulating cell-free DNA, most of the studies have focused on short DNA molecules (e.g.,

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Bibliographische Detailangaben
Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 2021-12, Vol.118 (50), p.1-11
Hauptverfasser:	Yu, Stephanie C. Y., Jiang, Peiyong, Peng, Wenlei, Cheng, Suk Hang, Cheung, Y. T. Tommy, Tse, O. Y. Olivia, Shang, Huimin, Poon, Liona C., Leung, Tak Y., Chan, K. C. Allen, Chiu, Rossa W. K., Lo, Y. M. Dennis
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological Sciences Cell-Free Nucleic Acids - blood Cell-Free Nucleic Acids - genetics Chromosomes - genetics Computer Simulation CpG islands Deoxyribonucleic acid Detection limits DNA DNA methylation DNA sequencing Female Fetus Fetuses Genomes Humans Maternal inheritance Plasma Pre-eclampsia Preeclampsia Pregnancy Recombination Single Molecule Imaging
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Beschreibung
Zusammenfassung:	In the field of circulating cell-free DNA, most of the studies have focused on short DNA molecules (e.g.,
ISSN:	0027-8424 1091-6490
DOI:	10.1073/pnas.2114937118