Transferable IgA-coated Odoribacter splanchnicus in Responders to Fecal Microbiota Transplantation for Ulcerative Colitis Limits Colonic Inflammation

Transferable IgA-coated Odoribacter splanchnicus in Responders to Fecal Microbiota Transplantation for Ulcerative Colitis Limits Colonic Inflammation

Fecal microbiota transplantation is an emerging therapy to treat ulcerative colitis. These findings define strain transferability associated with clinical response and highlight the mechanisms of their immune impact.

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Veröffentlicht in:Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 2021-10, Vol.162 (1), p.166-178
Hauptverfasser: Lima, Svetlana, Gogokhia, Lasha, Viladomiu, Monica, Chou, Lance, Putzel, Gregory, Jin, Wenbing, Pires, Silvia, Guo, Chun-Jun, Gerardin, Ylaine, Crawford, Carl V, Jacob, Vinita, Scherl, Ellen, Brown, Su-Ellen, Hambor, John, Longman, Randy
Format: Artikel
Sprache:eng
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Zusammenfassung:Fecal microbiota transplantation is an emerging therapy to treat ulcerative colitis. These findings define strain transferability associated with clinical response and highlight the mechanisms of their immune impact.
ISSN:0016-5085
1528-0012
DOI:10.1053/j.gastro.2021.09.061