Initial cancer treatment and survival in children, adolescents, and young adults with Hodgkin lymphoma: A population‐based study

Background Hodgkin lymphoma (HL) is a treatable tumor affecting children, adolescents and young adults (AYAs; 15‐39 years old). Population‐based studies report worse survival for non‐White children and AYAs but have limited data on individual therapeutic exposures. This study examined overall and HL‐specific survival in a population‐based cohort of patients while adjusting for sociodemographic factors and treatment. Methods Data for 4807 patients younger than 40 years with HL (2007‐2017) were obtained from the California Cancer Registry. Individual treatment information was extracted from text fields; chemotherapy regimens were defined by standard approaches for pediatric and adult HL. Multivariable Cox models examined the influence of patient and treatment factors on survival. Results At a median follow‐up of 4.4 years, 95% of the patients were alive. Chemotherapy differed by age, with 70% of 22‐ to 39‐year‐olds and 41% of