Increased Dosage of MRA Improves BP and Urinary Albumin Excretion in Primary Aldosteronism With Suppressed Plasma Renin

Abstract Purpose Excessive aldosterone secretion causes a high risk of cardio-cerebrovascular events. Mineralocorticoid receptor antagonist (MRA) is 1 of the treatment strategies for primary aldosteronism (PA). However, current MRA treatment is insufficient because MRA-treated patients with suppress...

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Veröffentlicht in:Journal of the Endocrine Society 2022-01, Vol.6 (1), p.bvab174-bvab174
Hauptverfasser: Saiki, Aya, Otsuki, Michio, Tamada, Daisuke, Kitamura, Tetsuhiro, Mukai, Kosuke, Yamamoto, Koichi, Shimomura, Iichiro
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Sprache:eng
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Zusammenfassung:Abstract Purpose Excessive aldosterone secretion causes a high risk of cardio-cerebrovascular events. Mineralocorticoid receptor antagonist (MRA) is 1 of the treatment strategies for primary aldosteronism (PA). However, current MRA treatment is insufficient because MRA-treated patients with suppressed plasma renin activity (PRA) 
ISSN:2472-1972
2472-1972
DOI:10.1210/jendso/bvab174