Clinical Characteristics and Outcomes of COVID-19 Patients Hospitalized in Intensive Care Unit

Meta-analysis and clinical studies suggest coronavirus disease-2019 (COVID-19) patients in ICU have a high mortality rate of 30-45%, which has evolved as a function of criteria of admission and the management modalities. We conducted a retrospective evaluation for characteristics and outcomes in cri...

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Veröffentlicht in:Indian journal of critical care medicine 2021-09, Vol.25 (9), p.992-1000
Hauptverfasser: Pandit, Rahul A, Gagana, B N, Vaity, Charudatt, Mulakavalupil, Bindu, Choudhary, Jitendra S, Jain, Vivek, Chandan, Pramila M, Joshi, Harsh
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Sprache:eng
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Zusammenfassung:Meta-analysis and clinical studies suggest coronavirus disease-2019 (COVID-19) patients in ICU have a high mortality rate of 30-45%, which has evolved as a function of criteria of admission and the management modalities. We conducted a retrospective evaluation for characteristics and outcomes in critical care set up across six months. 514 patients (74.3% males and 25.6% females) were evaluated. 9.72% ( = 50) patients expired, 78% ( = 39) were males. Mean age (years) was 57 (±14, range 64, 95% CI 55-58). 65.7% ( = 338) were of age more than 50 years, of which 71.5% ( = 242) were males. Males at 20% higher risk for death than women. (RR = 1.2, 95% CI 0.66-2.31, = 0.61 NS). There was 18% less risk of mortality in female vs male with comorbidities (RR 0.82, 95% CI 0.67-1.12, = 0.32 NS). Risk for mortality in diabetics was significantly increased by 116% vs nondiabetics. (RR 2.16, = 0.0055, 95% CI 1.28-3.67). Highly significant risk of mortality in age group >50 years (3.13 times higher) vs age ≤50 years. (RR 3.18, 95% CI 1.71-8.64, = 0.0003). 50.2% had moderate ARDS at admission. High flow nasal cannula was used in 47.2%. There is 5.79 times more likelihood to be on the ventilator with moderate to severe ARDS vs mild ARDS (RR = 5.79, 95% CI 3.10-11.05,
ISSN:0972-5229
1998-359X
DOI:10.5005/jp-journals-10071-23945