Changing trends in mortality among solid organ transplant recipients hospitalized for COVID‐19 during the course of the pandemic

Mortality among patients hospitalized for COVID‐19 has declined over the course of the pandemic. Mortality trends specifically in solid organ transplant recipients (SOTR) are unknown. Using data from a multicenter registry of SOTR hospitalized for COVID‐19, we compared 28‐day mortality between early...

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Veröffentlicht in:	American journal of transplantation 2022-01, Vol.22 (1), p.279-288
Hauptverfasser:	Heldman, Madeleine R., Kates, Olivia S., Safa, Kassem, Kotton, Camille N., Georgia, Sarah J., Steinbrink, Julie M., Blumberg, Emily A., Haydel, Brandy, La Hoz, Ricardo M., Moni, Lisset, Condor, Yesabeli, Flores, Sandra, Munoz, Carlos G., Guitierrez, Juan, Diaz, Esther I., Vianna, Rodrigo, Loebe, Matthias, Rakita, Robert M., Malinis, Maricar, Azar, Marwan M., McCort, Margaret E., Chaudhry, Zohra S., Velioglu, Arzu, Yabu, Julie M., Mehta, Sapna A., Tanna, Sajal D., Ison, Michael G., Derenge, Ariella C., Duin, David, Goldman, Jason D., Fisher, Cynthia E., Limaye, Ajit P., De la Cruz, Oveimar, Besharatian, Behdad D., Sehgal, Sameep, Weisshaar, Dana, Girgis, Reda, Lawrence, Cameron, Bennett, William, Leandro, Jennifer, Sait, Afrah, Rumore, Amy, West, Patricia, Jeng, Amy, Bajrovic, Valida, Bilgili, Erin P., Nastase, Abigail, Badami, Abbas, Alvarez‐Garcia, Jesus, Bowman‐Anger, Lyndsey, Julien, Lovelyn, Ortiz‐Bautista, Carlos, Friedman‐Morocco, Rachel, Gajurel, Kiran, Cahuayme‐Zuniga, Lizbeth, Wakefield, Mark, Theodoropoulos, Nicole, Chopra, Bhavna, Florescu, Diana, Witteck, Danielle, Diaz, Daniela, Ripley, Kathryn, Saharia, Kapil, Webb, Ally, Arya, Akanksha, Vedula, Giridhar, El‐Amm, Jose‐Marie, Narayanan, Arun, Cilene Leon Bueno de Camargo, Priscila, Ouseph, Rosemary, Luk, Alfred, Aujayeb, Avinash, Ganger, Daniel, Keith, Douglas S., Meloni, Federica, Haidar, Ghady, Zapernick, Lori, Moraels, Megan, Goyal, Nitender, Sharma, Tanvi, Rossi, Ana P., Keller, Brian, Carlson, Elise, Hashim, Faris, Murad, Haris, Wilkens, Heinrike, Neumann, Henry, Gani, Imran, Kahwaji, Joseph, Jakharia, Niyati, Puing, Alfredo, Motallebzadeh, Reza, Velagapudi, Ravi, Kapoor, Rajan, Vora, Surabhi, Kelly, Ursala M., Reddy, Uttam, Dharnidharka, Vikas, Wadei, Hani, Zurabi, Lominadze
Format:	Artikel
Sprache:	eng
Schlagworte:	Antiviral drugs Brief Communication Brief Communications clinical research/practice Corticosteroids COVID-19 Dexamethasone Hospitalization Humans Hydroxychloroquine infection and infectious agents ‐ viral infectious disease Mortality Organ Transplantation - adverse effects organ transplantation in general Pandemics Quality of care quality of care/care delivery SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 Transplant Recipients Transplants & implants Trends
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Zusammenfassung:	Mortality among patients hospitalized for COVID‐19 has declined over the course of the pandemic. Mortality trends specifically in solid organ transplant recipients (SOTR) are unknown. Using data from a multicenter registry of SOTR hospitalized for COVID‐19, we compared 28‐day mortality between early 2020 (March 1, 2020–June 19, 2020) and late 2020 (June 20, 2020–December 31, 2020). Multivariable logistic regression was used to assess comorbidity‐adjusted mortality. Time period of diagnosis was available for 1435/1616 (88.8%) SOTR and 971/1435 (67.7%) were hospitalized: 571/753 (75.8%) in early 2020 and 402/682 (58.9%) in late 2020 (p
ISSN:	1600-6135 1600-6143 1600-6143
DOI:	10.1111/ajt.16840