Pulmonary function and functional capacity cut-off point to establish sarcopenia and dynapenia in patients with COPD

To establish a cut-off point for clinical and functional variables to determinate sarcopenia and dynapenia in COPD patients, and to analyze the impact of skeletal muscle dysfunction (SMD) on these variables. Cross-sectional study, screened COPD patients for sarcopenia or dynapenia through low muscle...

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Veröffentlicht in:Jornal brasileiro de pneumologia 2019-01, Vol.45 (6), p.e20180252-e20180252
Hauptverfasser: Mansour, Kamila Mohammad Kamal, Goulart, Cássia da Luz, Carvalho-Junior, Luiz Carlos Soares de, Trimer, Renata, Borghi-Silva, Audrey, Silva, Andréa Lúcia Gonçalves da
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Zusammenfassung:To establish a cut-off point for clinical and functional variables to determinate sarcopenia and dynapenia in COPD patients, and to analyze the impact of skeletal muscle dysfunction (SMD) on these variables. Cross-sectional study, screened COPD patients for sarcopenia or dynapenia through low muscle mass and hand grip strength (HGS). Clinical variables: pulmonary function, respiratory muscle strength and functional capacity (FC). The precision of the variables in determining points of predictive cut-off for sarcopenia or dynapenia were performed using the Receiver Operating Characteristic curve and two-way analysis of variance. 20 COPD patients stratified for sarcopenia (n = 11) and dynapenia (n = 07). Sarcopenia group presented lower lean mass and lower maximal inspiratory pressure (MIP), decreased HGS, reduced FC (p
ISSN:1806-3713
1806-3756
DOI:10.1590/1806-3713/e20180252