Development of a Purified Viral Preparation for Studies of COVID-19 (SARS-CoV-2) Biology

Different methods for producing bulk quantities of concentrated and purified SARS-CoV-2 for the use as antigens and for the research into COVID-19 biology were tested.

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Bibliographische Detailangaben
Veröffentlicht in:	Bulletin of experimental biology and medicine 2021-11, Vol.172 (1), p.49-52
Hauptverfasser:	Chepurnov, A. A., Kazachinskaya, E. I., Kazachkova, E. A., Sharshov, K. A., Kononova, Yu. V., Shelemba, A. A., Alekseev, A. Yu, Gulyeva, M. A., Voevoda, M. I., Shestopalov, A. M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies Antibodies, Neutralizing - isolation & purification Antibodies, Neutralizing - metabolism Antibodies, Viral - isolation & purification Antibodies, Viral - metabolism Antigens Biomedical and Life Sciences Biomedicine Cell Biology Cell Line Chlorocebus aethiops Convalescence Coronaviruses COVID-19 COVID-19 - diagnosis COVID-19 - virology COVID-19 Testing - methods Epithelial Cells - virology Health aspects Humans Immune Sera - chemistry Internal Medicine Laboratory Medicine Pathology Proteins SARS-CoV-2 - genetics SARS-CoV-2 - growth & development SARS-CoV-2 - immunology Severe acute respiratory syndrome coronavirus 2 Swine Vaccines Vero Cells Viral antibodies Viral Load - genetics Viral Load - immunology Viral Proteins - immunology Viral Proteins - isolation & purification Viral Proteins - metabolism Virion - genetics Virion - growth & development Virion - immunology Virology Virus Replication
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Beschreibung
Zusammenfassung:	Different methods for producing bulk quantities of concentrated and purified SARS-CoV-2 for the use as antigens and for the research into COVID-19 biology were tested.
ISSN:	0007-4888 1573-8221
DOI:	10.1007/s10517-021-05329-7