Ultrasound Effectiveness of Steroid Injection for hand Psoriatic Dactylitis: Results from a Longitudinal Observational Study

Introduction To assess clinical and ultrasound effectiveness of steroid injection (local treatment, LT) into the digital flexor tendon sheath for the treatment of psoriatic dactylitis compared to systemic treatment (ST) alone. Methods In this observational, multicentre, prospective study, 88 cases o...

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Veröffentlicht in:Rheumatology and Therapy 2021-12, Vol.8 (4), p.1809-1826
Hauptverfasser: Girolimetto, Nicolò, Macchioni, Pierluigi, Tinazzi, Ilaria, Possemato, Niccolò, Costa, Luisa, Bascherini, Vittoria, Peluso, Rosario, Citriniti, Giorgia, Galletto, Giulia, Martinis, Federica, Marchetta, Antonio, Sabbatino, Vincenzo, Tasso, Marco, Passavanti, Saverio, Salvarani, Carlo, Scarpa, Raffaele, Caso, Francesco
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Sprache:eng
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Zusammenfassung:Introduction To assess clinical and ultrasound effectiveness of steroid injection (local treatment, LT) into the digital flexor tendon sheath for the treatment of psoriatic dactylitis compared to systemic treatment (ST) alone. Methods In this observational, multicentre, prospective study, 88 cases of symptomatic hand dactylitis were evaluated clinically and sonographically by high-frequency ultrasound (US) probe in both greyscale (GS) and power Doppler (PD). The presence of flexor tenosynovitis (FT), soft tissue oedema (STO), peritendon extensor inflammation and synovitis was assessed (including DACtylitis glObal Sonographic—DACTOS—score) before treatment, at 1-month (T1) and 3-months (T3) follow-up. LT was proposed to all patients. Patients refusing LT were treated with oral NSAIDs. Patients continued the same baseline csDMARDs and/or corticosteroid therapy during the whole follow-up period. US response was defined for DACTOS score  1) of FT and STO ( p  
ISSN:2198-6576
2198-6584
DOI:10.1007/s40744-021-00383-z