Divergent humoral responses in mild to moderate SARS-CoV-2 infection over time – indication of persistence of the virus?

-Detailed longitudinal serological description (14 month) of mild to moderate COVID-19.-All participants followed for 14 month showed antibodies at the final study visit.-Anti-spike IgG is initially gender dependent and switches to age dependence.-The anti-spike IgA levels of the majority of partici...

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Veröffentlicht in:	The Journal of infection 2022-03, Vol.84 (3), p.418-467
Hauptverfasser:	Bürgi, Justus J., Rösslein, Matthias, Hornung, Henry, Jentsch, Jana, Boller, Viveka L., Dollenmaier, Günter, Wick, Peter, Peier, Karen, Nohynek, Brigitte, Fischer, Aldo, Stolz, Raphael, Cettuzzi, Michele, Reut, Michael, Boy, Regine Garcia, Nolte, Oliver, Korte, Wolfgang
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antibodies, Neutralizing Antibodies, Viral COVID-19 Humans IgA Immunity, Humoral Immunoglobulin A Letter to the Editor SARS-CoV-2 Serology
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	-Detailed longitudinal serological description (14 month) of mild to moderate COVID-19.-All participants followed for 14 month showed antibodies at the final study visit.-Anti-spike IgG is initially gender dependent and switches to age dependence.-The anti-spike IgA levels of the majority of participants are gradually increasing.-The results are indicating a subtle anti-spike IgA stimulus. [Display omitted]
ISSN:	0163-4453 1532-2742
DOI:	10.1016/j.jinf.2021.11.001