Postloading insulinemia is independently associated with arterial stiffness in young Japanese persons

Postloading insulinemia is independently associated with arterial stiffness in young Japanese persons

Associations of arterial stiffness with glucose, insulin, and proinsulin dynamics during the oral glucose tolerance test (OGTT) remain under debate. The aim of this study was to investigate whether plasma glucose (PG), insulin, and proinsulin (Pro) contribute to arterial stiffness, measured by pulse...

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Veröffentlicht in:Hypertension research 2021-11, Vol.44 (11), p.1515-1523
Hauptverfasser: Murai, Norimitsu, Saito, Naoko, Nii, Sayuri, Nishikawa, Yuto, Suzuki, Asami, Kodama, Eriko, Iida, Tatsuya, Mikura, Kentaro, Imai, Hideyuki, Hashizume, Mai, Kigawa, Yasuyoshi, Tadokoro, Rie, Sugisawa, Chiho, Endo, Kei, Iizaka, Toru, Otsuka, Fumiko, Ishibashi, Shun, Nagasaka, Shoichiro
Format: Artikel
Sprache:eng
Schlagworte:
Blood Glucose
Cardiovascular disease
Glucose
Humans
Hypertension
Insulin
Insulin Resistance
Japan
Male
Pulse Wave Analysis
Vascular Stiffness
Young adults
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Zusammenfassung:Associations of arterial stiffness with glucose, insulin, and proinsulin dynamics during the oral glucose tolerance test (OGTT) remain under debate. The aim of this study was to investigate whether plasma glucose (PG), insulin, and proinsulin (Pro) contribute to arterial stiffness, measured by pulse wave velocity (PWV), in young Japanese persons. PG, immunoreactive insulin (IRI), and Pro levels were determined in 1193 young Japanese subjects (
ISSN:0916-9636
1348-4214
DOI:10.1038/s41440-021-00749-4