Complexities in estimating the true risk of hereditary leiomyomatosis and renal cell carcinoma and the development of kidney cancer

Currently, the incidence of hereditary leiomyomatosis and renal cell cancer (HLRCC), as well as the penetrance of kidney cancer among patients with HLRCC, is unknown. Large‐scale genomic databases may be unable to accurately estimate the incidence of HLRCC.

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Bibliographische Detailangaben
Veröffentlicht in:	Cancer 2020-08, Vol.126 (16), p.3617-3619
Hauptverfasser:	Ball, Mark W., Ricketts, Christopher J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer cancer genetics Carcinoma, Renal Cell - complications Carcinoma, Renal Cell - genetics Carcinoma, Renal Cell - pathology Fibroids Fumarate Hydratase - genetics Genetic Predisposition to Disease hereditary hereditary leiomyomatosis and renal cell cancer HLRCC Humans Kidney cancer Kidney Neoplasms - etiology Kidney Neoplasms - genetics Kidney Neoplasms - pathology Kidneys Leiomyomatosis - complications Leiomyomatosis - genetics Leiomyomatosis - pathology Neoplastic Syndromes, Hereditary - complications Neoplastic Syndromes, Hereditary - genetics Neoplastic Syndromes, Hereditary - pathology Renal cell carcinoma Skin Neoplasms - complications Skin Neoplasms - genetics Skin Neoplasms - pathology Uterine Neoplasms - complications Uterine Neoplasms - genetics Uterine Neoplasms - pathology
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Beschreibung
Zusammenfassung:	Currently, the incidence of hereditary leiomyomatosis and renal cell cancer (HLRCC), as well as the penetrance of kidney cancer among patients with HLRCC, is unknown. Large‐scale genomic databases may be unable to accurately estimate the incidence of HLRCC.
ISSN:	0008-543X 1097-0142
DOI:	10.1002/cncr.32915