Comparison of 30-day case-fatality rate between dialysis and transplant Covid-19 patients: a propensity score matched cohort study

Background and objectives Patients undergoing kidney replacement therapies (KRTs) have a poor prognosis after Covid-19 infection. Few studies have compared the outcomes of such patients in the different KRT modalities. This study aimed to analyze the 30-day Covid-19-associated case-fatality rate of...

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Veröffentlicht in:Journal of nephrology 2022-01, Vol.35 (1), p.131-141
Hauptverfasser: de Sandes-Freitas, Tainá Veras, de Andrade, Luís Gustavo Modelli, Moura, Lucio Roberto Requião, Cristelli, Marina Pontello, Medina-Pestana, José Osmar, Lugon, Jocemir Ronaldo, Sesso, Ricardo
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Sprache:eng
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Zusammenfassung:Background and objectives Patients undergoing kidney replacement therapies (KRTs) have a poor prognosis after Covid-19 infection. Few studies have compared the outcomes of such patients in the different KRT modalities. This study aimed to analyze the 30-day Covid-19-associated case-fatality rate of dialysis and kidney transplant patients. Methods Retrospective cohort study analyzing data from patients with confirmed Covid-19 between Mar/20 and Jan/21 included in two multicenter studies, the Brazilian Covid-19 Dialysis Study (Dialysis group, n  = 703) and the Covid-19-KT Brazilian Study (Transplant group, n  = 1907). To assess the risk factors for death, adjusted Cox hazards models were used. A sensitivity analysis was performed using a propensity score analysis to match the groups ( n  = 587 patients in each group). Results A higher percentage of transplant patients required hospitalization (68 vs. 51%, p  
ISSN:1121-8428
1724-6059
DOI:10.1007/s40620-021-01172-1