Association Between Increased Seizures During Rewarming After Hypothermia for Neonatal Hypoxic Ischemic Encephalopathy and Abnormal Neurodevelopmental Outcomes at 2-Year Follow-up: A Nested Multisite Cohort Study

This cohort study evaluates whether electrographic seizures are more likely to occur during rewarming compared with the preceding period and whether they are associated with abnormal outcomes in asphyxiated neonates receiving hypothermia therapy.

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Veröffentlicht in:JAMA neurology 2021-10, Vol.78 (12), p.1-10
Hauptverfasser: Chalak, Lina F., Pappas, Athina, Tan, Sylvia, Das, Abhik, Sánchez, Pablo J., Laptook, Abbot R., Van Meurs, Krisa P., Shankaran, Seetha, Bell, Edward F., Davis, Alexis S., Heyne, Roy J., Pedroza, Claudia, Poindexter, Brenda B., Schibler, Kurt, Tyson, Jon E., Ball, M. Bethany, Bara, Rebecca, Grisby, Cathy, Sokol, Gregory M., D’Angio, Carl T., Hamrick, Shannon E. G., Dysart, Kevin C., Cotten, C. Michael, Truog, William E., Watterberg, Kristi L., Timan, Christopher J., Garg, Meena, Carlo, Waldemar A., Higgins, Rosemary D.
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Sprache:eng
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Zusammenfassung:This cohort study evaluates whether electrographic seizures are more likely to occur during rewarming compared with the preceding period and whether they are associated with abnormal outcomes in asphyxiated neonates receiving hypothermia therapy.
ISSN:2168-6149
2168-6157
DOI:10.1001/jamaneurol.2021.3723