Elevated 2HG does not cause features of tumorigenesis

Abstract Aims Gliomas are the most frequent brain tumours, representing 75% of all primary malignant brain tumours in adults. IDH1 (and IDH2) driver mutations occur in >80% of low grade gliomas and secondary GBMs, in

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Veröffentlicht in:Neuro-oncology (Charlottesville, Va.) Va.), 2021-10, Vol.23 (Supplement_4), p.iv1-iv1
Hauptverfasser: Adam, Julie, Finch, Alina, Sepulveda, Catarina, Ducker, Martin, Torroba, Maria Blanca, Krell, Daniel, Kriaucionis, Skirmantas, Szele, Francis, Ratcliffe, Peter, Soga, Tomoyoshi, Kranc, Kamil, Tomlinson, Ian, Bardella, Chiara
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Sprache:eng
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Zusammenfassung:Abstract Aims Gliomas are the most frequent brain tumours, representing 75% of all primary malignant brain tumours in adults. IDH1 (and IDH2) driver mutations occur in >80% of low grade gliomas and secondary GBMs, in
ISSN:1522-8517
1523-5866
DOI:10.1093/neuonc/noab195.000