Assessment of bone quality with trabecular bone score in patients with inflammatory bowel disease

Inflammatory bowel disease (IBD) patients have a significant risk of developing bone loss. The trabecular bone score (TBS) is a relatively new parameter used to provide information on bone quality. The study cohort included 81 patients with IBD and 81 healthy controls. Blood tests, dual-energy x-ray...

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Veröffentlicht in:Scientific reports 2021-10, Vol.11 (1), p.20345-20345, Article 20345
Hauptverfasser: Soare, Iulia, Sirbu, Anca, Martin, Sorina, Diculescu, Mircea, Mateescu, Bogdan, Tieranu, Cristian, Fica, Simona
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Sprache:eng
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Zusammenfassung:Inflammatory bowel disease (IBD) patients have a significant risk of developing bone loss. The trabecular bone score (TBS) is a relatively new parameter used to provide information on bone quality. The study cohort included 81 patients with IBD and 81 healthy controls. Blood tests, dual-energy x-ray absorptiometry (DXA), including TBS, were assessed. Harvey–Bradshaw Index (HBI) for Crohn's disease (CD) and the Partial Mayo Score for ulcerative colitis (UC) were used for evaluation of clinical disease activity. Compared with the healthy controls, the IBD patients had lower lumbar spine (LS) bone mineral density (BMD) (1.06 ± 0.18 vs. 1.16 ± 0.15 g/cm 2 , p  
ISSN:2045-2322
2045-2322
DOI:10.1038/s41598-021-99669-z