PSIX-23 Correlation between VRTN and PPARD gene variants and the phenotypic manifestation of productive traits and the hind limbs conformation in pigs

Abstract We formed three samples: Landrace (L, n = 86), Large White (LW, n = 120), and Duroc pigs (D, n = 140). Three traits investigated: the mean daily gain (ADG), early maturity (DAY100) and limb condition (LEG; good/bad). The PPARD (rs80828473) and VRTN (rs343248943) genes were selected. The effects of genotypes PPARD on ADG and DAY100 were determined in Duroc by the association with these traits. Pigs D of AA, comparing to GG had better ADG by 82.3 (P = 0.01) and DAY100 by 6.5 (P = 0.05). Pigs L with the AA genotype, comparing to the GG genotype, had the best ADGs by 101.0 (P = 0.05) and DAY100 by 13.1 (P = 0.04). The effect of the PPARD in LW is unknown as AA genotype was not detected in LW. For the VRTN gene D pigs of the AG and GG genotype comparing to the AA genotype had the best ADGs by 49.1 (P = 0.03) and 56.5 (P = 0.09); DAY100 by 4.8 (P = 0.03) and 9.7 (P = 0.005). Pigs D of AA genotype (P = 0.01) had the best limbs conformation but demonstrated lower productivity. In Landrace pigs, no differences in ADG and DAY100 associated with the VRTN genotypes were found. The possible reason is the low frequency of the GG genotype in this group. Regarding to the limbs the desired genotype in pigs L is AA (P = 0.05). In Large white pigs a positive effect of the AG genotype on ADG and DAY100 was found, comparing to the AA genotype it was 100.6 g (P = 0.02) and 11.7 days. (P = 0.01). The effect of the VRTN different genotypes on the LW limbs has not been found. Research was performed with the Russian Foundation for Basic Research financial support 19-016-00068 A.