A vast pool of lineage-specific microproteins encoded by long non-coding RNAs in plants

A vast pool of lineage-specific microproteins encoded by long non-coding RNAs in plants

Pervasive transcription of eukaryotic genomes results in expression of long non-coding RNAs (lncRNAs) most of which are poorly conserved in evolution and appear to be non-functional. However, some lncRNAs have been shown to perform specific functions, in particular, transcription regulation. Thousan...

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Veröffentlicht in:Nucleic acids research 2021-10, Vol.49 (18), p.10328-10346
Hauptverfasser: Fesenko, Igor, Shabalina, Svetlana A, Mamaeva, Anna, Knyazev, Andrey, Glushkevich, Anna, Lyapina, Irina, Ziganshin, Rustam, Kovalchuk, Sergey, Kharlampieva, Daria, Lazarev, Vassili, Taliansky, Michael, Koonin, Eugene V
Format: Artikel
Sprache:eng
Schlagworte:
Bryopsida - genetics
Computational Biology
Open Reading Frames
Proteome
RNA, Long Noncoding
Transcriptome
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Zusammenfassung:Pervasive transcription of eukaryotic genomes results in expression of long non-coding RNAs (lncRNAs) most of which are poorly conserved in evolution and appear to be non-functional. However, some lncRNAs have been shown to perform specific functions, in particular, transcription regulation. Thousands of small open reading frames (smORFs,
ISSN:0305-1048
1362-4962
DOI:10.1093/nar/gkab816