Association between biochemical hyperandrogenism parameters and modified Ferriman-Gallwey score in patients with hirsutism in Basrah (Southern Iraq)
Hyperandrogenemia is the most frequent endocrine disorder in women causing a variety of adverse metabolic disturbances. Establishing the diagnosis of androgen overproduction has significant implications for the follow-up and treatment of patients. To investigate the severity of hirsutism and its cor...
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Veröffentlicht in: | Postȩpy dermatologii i alergologii 2021-01, Vol.38 (4), p.603-607 |
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Sprache: | eng |
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Zusammenfassung: | Hyperandrogenemia is the most frequent endocrine disorder in women causing a variety of adverse metabolic disturbances. Establishing the diagnosis of androgen overproduction has significant implications for the follow-up and treatment of patients.
To investigate the severity of hirsutism and its correlation with serum androgen in women with hirsutism from Basrah (Southern Iraq).
This was a cross-sectional study of 300 hirsute women, mean age: 26.6 ±7.1 years with a modified Ferriman and Gallwey (mFG) score of 8 or higher. Assessment of hirsutism severity was performed and hormonal markers including total testosterone (TT), calculated free testosterone (FT) and dehydroepiandrosterone sulfate (DHEA-S), were measured.
There was a significant correlation between the severity of hirsutism using mFG score and FT, TT levels (
< 0.001 and
< 0.047, respectively), while no association was seen between mFG score and DHEA-S.
Our data suggest that FT and, to a less extent, TT were important biochemical hyperandrogenism markers that correlate with severity of hirsutism. DHEA-S was not found to be beneficial. |
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ISSN: | 1642-395X 2299-0046 |
DOI: | 10.5114/ada.2021.108907 |