Open-label phase 3 study of intravenous golimumab in patients with polyarticular juvenile idiopathic arthritis

Abstract Objectives To assess efficacy, pharmacokinetics (PK) and safety of intravenous (i.v.) golimumab in patients with polyarticular-course JIA (pc-JIA). Methods Children aged 2 to

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Veröffentlicht in:	Rheumatology (Oxford, England) England), 2021-10, Vol.60 (10), p.4495-4507
Hauptverfasser:	Ruperto, Nicolino, Brunner, Hermine I, Pacheco-Tena, César, Louw, Ingrid, Vega-Cornejo, Gabriel, Spindler, Alberto J, Kingsbury, Daniel J, Schmeling, Heinrike, Borzutzky, Arturo, Cuttica, Rubén, Inman, C J, Malievskiy, Victor, Scott, Christiaan, Keltsev, Vladimir, Terreri, Maria Teresa, Viola, Diego Oscar, Xavier, Ricardo M, Fernandes, Taciana A Pedrosa, Velázquez, María del Rocío Maldonado, Henrickson, Michael, Clark, Michael B, Bensley, Karen A, Li, Xiaoming, Lo, Kim Hung, Leu, Jocelyn H, Hsu, Chyi-Hung, Hsia, Elizabeth C, Xu, Zhenhua, Martini, Alberto, Lovell, Daniel J
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Intravenous Adolescent Antibodies, Monoclonal - administration & dosage Antirheumatic Agents - administration & dosage Arthritis - drug therapy Arthritis, Juvenile - drug therapy Child Child, Preschool Clinical Science Female Humans Male Treatment Outcome
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Beschreibung
Zusammenfassung:	Abstract Objectives To assess efficacy, pharmacokinetics (PK) and safety of intravenous (i.v.) golimumab in patients with polyarticular-course JIA (pc-JIA). Methods Children aged 2 to
ISSN:	1462-0324 1462-0332
DOI:	10.1093/rheumatology/keab021