Analysis of Using the Total White Blood Cell Count to Define Severe New‐onset Ulcerative Colitis in Children

Analysis of Using the Total White Blood Cell Count to Define Severe New‐onset Ulcerative Colitis in Children

ABSTRACT Objectives: The aim of this study was to assess common laboratory tests in identifying severe ulcerative colitis in children at diagnosis. Methods: A cohort of 427 children 4 to 17 years of age newly diagnosed with ulcerative colitis (UC) was prospectively enrolled. Boosted classification t...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of pediatric gastroenterology and nutrition 2020-09, Vol.71 (3), p.354-360
Hauptverfasser: Mack, David R., Saul, Bradley, Boyle, Brendan, Griffiths, Anne, Sauer, Cary, Markowitz, James, LeLeiko, Neal, Keljo, David, Rosh, Joel R., Baker, Susan S., Steiner, Steve, Heyman, Melvin B., Patel, Ashish S., Baldassano, Robert, Noe, Joshua, Rufo, Paul, Kugathasan, Subra, Walters, Thomas, Marquis, Alison, Thomas, Sonia M., Denson, Lee, Hyams, Jeffrey
Format: Artikel
Sprache:eng
Schlagworte:
classification tree analysis
inflammatory bowel disease
laboratory values
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:ABSTRACT Objectives: The aim of this study was to assess common laboratory tests in identifying severe ulcerative colitis in children at diagnosis. Methods: A cohort of 427 children 4 to 17 years of age newly diagnosed with ulcerative colitis (UC) was prospectively enrolled. Boosted classification trees were used to characterize predictive ability of disease attributes based on clinical disease severity using Pediatric Ulcerative Colitis Activity Index (PUCAI), severe (65+) versus not severe (
ISSN:0277-2116
1536-4801
DOI:10.1097/MPG.0000000000002797