Relatively low and moderate pre-fracture serum 25-hydroxyvitamin D levels associated with the highest survival in elderly hip fracture patients in Finland: a minimum 3-year follow-up

Summary The association between serum 25-hydroxyvitamin D level and post-fracture mortality indicates beneficial relatively high serum 25-hydroxyvitamin D concentrations. A 1-year cohort study on 245 hip fracture patients in Finland indicated the lowest 3-year mortality and highest survival among pa...

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Veröffentlicht in:Osteoporosis international 2022-03, Vol.33 (3), p.611-621
Hauptverfasser: Nurmi-Lüthje, I., Tiihonen, R., Paattiniemi, E-L., Sarkkinen, H., Naboulsi, H., Pigg, S., Kaukonen, J-P., Kataja, M., Lüthje, P.
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Sprache:eng
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Zusammenfassung:Summary The association between serum 25-hydroxyvitamin D level and post-fracture mortality indicates beneficial relatively high serum 25-hydroxyvitamin D concentrations. A 1-year cohort study on 245 hip fracture patients in Finland indicated the lowest 3-year mortality and highest survival among patients with serum 25-hydroxyvitamin D level of 50–74 nmol/L. Purpose To explore pre-fracture serum 25-hydroxyvitamin D level as a factor associated with post-fracture survival among a cohort of hip fracture patients in Finland. Methods A prospectively collected cohort of hip fracture patients ( n  = 245, 70% women) from two hospitals was followed for 3.2 post-hip fracture years. Serum 25-hydroxyvitamin D was measured in admission to the hospital and classified: 
ISSN:0937-941X
1433-2965
DOI:10.1007/s00198-021-06094-z