Circular RNA circHIPK3 promotes homeostasis of the intestinal epithelium by reducing miR-29b function

Circular RNA circHIPK3 promotes homeostasis of the intestinal epithelium by reducing miR-29b function

Circular RNA circHIPK3 enhances intestinal epithelial repair and promotes mucosal growth by reducing microRNA 29b activity, but its levels decrease in IBD patients.

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Veröffentlicht in:Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 2021-06, Vol.161 (4), p.1303-1317.e3
Hauptverfasser: Xiao, Lan, Ma, Xiang-Xue, Luo, Jason, Chung, Hee K., Kwon, Min S., Yu, Ting-Xi, Rao, Jaladanki N., Kozar, Rosemary, Gorospe, Myriam, Wang, Jian-Ying
Format: Artikel
Sprache:eng
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Zusammenfassung:Circular RNA circHIPK3 enhances intestinal epithelial repair and promotes mucosal growth by reducing microRNA 29b activity, but its levels decrease in IBD patients.
ISSN:0016-5085
1528-0012
DOI:10.1053/j.gastro.2021.05.060