Preclinical ocular features in patients with Behçet’s disease detected by optical coherence tomography angiography

Objective The aim of this study was to evaluate the perifoveal and peripapillary microvascular structure in patients with Behçet’s disease (BD) without clinically ocular involvement. Methods Fifty-six eyes of 28 patients with Behçet’s disease without clinically ocular involvement and 50 age-matched healthy eyes were included in this prospective study. Vessel densities (VD) of macula and optic nerve head, foveal avascular zone (FAZ), choroid capillary plexus (CCP) flow area, perifoveal capillary nonperfusion, capillary dilatation and/or telangiectasia and perifoveal capillary arcade disruption were analyzed with optical coherence tomography angiography (OCTA). The relationship between duration of disease and vessel densities was also evaluated. Results The FAZ was significantly higher in the BD group ( p