Lessons of the month 1: Longitudinal extensive transverse myelitis following AstraZeneca COVID-19 vaccination

Longitudinal extensive transverse myelitis (LETM) is a rare but recognised complication of vaccination. We report the case of a 58-year-old man admitted to hospital 10 days after his first AstraZeneca COVID-19 vaccination with progressive neurological symptoms and signs, and investigations and imagi...

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Veröffentlicht in:Clinical medicine (London, England) England), 2021-09, Vol.21 (5), p.e535-e538
Hauptverfasser: Notghi, Alp AA, Atley, Joseph, Silva, Mark
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creator Notghi, Alp AA
Atley, Joseph
Silva, Mark
description Longitudinal extensive transverse myelitis (LETM) is a rare but recognised complication of vaccination. We report the case of a 58-year-old man admitted to hospital 10 days after his first AstraZeneca COVID-19 vaccination with progressive neurological symptoms and signs, and investigations and imaging consistent with LETM. This case reviews the literature and the investigative process behind excluding other diagnoses given the patient’s background of pulmonary sarcoidosis. It is unique in being the first UK report of a case of LETM with a strong temporal link to COVID-19 vaccination.
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subjects AstraZeneca
Coronaviruses
COVID-19
COVID-19 Vaccines
Diabetes
Humans
Influenza
Lessons of the Month
longitudinal extensive transverse myelitis
Magnetic resonance imaging
Male
Middle Aged
Multiple sclerosis
myelitis
Myelitis, Transverse - chemically induced
Myelitis, Transverse - drug therapy
Sarcoidosis
SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2
Steroids
vaccination
Vaccination - adverse effects
title Lessons of the month 1: Longitudinal extensive transverse myelitis following AstraZeneca COVID-19 vaccination
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