Biofabrication of a Low Modulus Bioelectroprobe for Neurons to Grow Into

Implantable nerve electrodes, as a bridge between the brain and external devices, have been widely used in areas such as brain function exploration, neurological disease treatment and human–computer interaction. However, the mechanical properties mismatch between the electrode material and the brain...

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Veröffentlicht in:Materials 2021-08, Vol.14 (16), p.4718
Hauptverfasser: Hao, Zhiyan, Wang, Sen, Zhang, Kun, Zhou, Jiajia, Li, Dichen, He, Jiankang, Gao, Lin, Wang, Ling
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Sprache:eng
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Zusammenfassung:Implantable nerve electrodes, as a bridge between the brain and external devices, have been widely used in areas such as brain function exploration, neurological disease treatment and human–computer interaction. However, the mechanical properties mismatch between the electrode material and the brain tissue seriously affects the stability of electrode signal acquisition and the effectiveness of long-term service in vivo. In this study, a modified neuroelectrode was developed with conductive biomaterials. The electrode has good biocompatibility and a gradient microstructure suitable for cell growth. Compared with metal electrodes, bioelectrodes not only greatly reduced the elastic modulus (
ISSN:1996-1944
1996-1944
DOI:10.3390/ma14164718