Household level SARS-CoV-2 sero-epidemiology in a high prevalence group of adults and children-implications for community infection control

•Children 10 year and younger are less likely to show evidence of SARS-CoV-2 infection in a household.•Most households have concordant SARS-CoV-2 serostatus between adults and children/adolescents but similar numbers have only a child/adolescent or an adult seropositive.•Households with both adults...

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Veröffentlicht in:American journal of infection control 2021-11, Vol.49 (11), p.1438-1440
Hauptverfasser: Werzberger, Alan, Carreño, Juan Manuel, Team, Sinai Serocore, Polinger, Adam, Krammer, Florian, Zachariah, Philip
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Sprache:eng
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Zusammenfassung:•Children 10 year and younger are less likely to show evidence of SARS-CoV-2 infection in a household.•Most households have concordant SARS-CoV-2 serostatus between adults and children/adolescents but similar numbers have only a child/adolescent or an adult seropositive.•Households with both adults and children/adolescents positive tend to be larger and have older children. In 108 households (n = 474, 280 ≤ 18 years old), SARS-CoV-2 seroprevalence was significantly associated with age (range 37.5%-78.7%) and lowest in children ≤ 10 years old. Among 92 households with members ≤ 18, 14 (15.2%) had only a seropositive child or adolescent, while 16 (17.4%) had only seropositive adults. Households with both groups concurrently seropositive (n = 62) were larger in size (mean 8.11 ± 2.49) vs (mean 5.77 ± 2.31) (P < .001).
ISSN:0196-6553
1527-3296
DOI:10.1016/j.ajic.2021.08.015