Predictive value of preoperative serum squamous cell carcinoma antigen level for lymph node metastasis in early-stage cervical squamous cell carcinoma

To explore the predictive value of preoperative serum squamous cell carcinoma antigen (SCC-Ag) level for lymph node metastasis (LNM), particularly, in patients surgically treated for early-stage cervical squamous cell carcinoma.We enrolled 162 patients with cervical squamous cell carcinoma stages IB...

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Veröffentlicht in:	Medicine (Baltimore) 2021-08, Vol.100 (33), p.e26960-e26960
Hauptverfasser:	Zhu, Chenggong, Zhang, Wenqing, Wang, Xiuying, Jiao, Lanzhou, Chen, Liyan, Jiang, Jiyong
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antigens, Neoplasm - blood Carcinoma, Squamous Cell - blood Carcinoma, Squamous Cell - diagnosis Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - surgery Female Humans Lymphatic Metastasis - diagnosis Lymphatic Metastasis - pathology Middle Aged Neoplasm Staging Observational Study Predictive Value of Tests Serpins - blood Uterine Cervical Neoplasms - blood Uterine Cervical Neoplasms - diagnosis Uterine Cervical Neoplasms - pathology Uterine Cervical Neoplasms - surgery
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Zusammenfassung:	To explore the predictive value of preoperative serum squamous cell carcinoma antigen (SCC-Ag) level for lymph node metastasis (LNM), particularly, in patients surgically treated for early-stage cervical squamous cell carcinoma.We enrolled 162 patients with cervical squamous cell carcinoma stages IB to IIA following the International Federation of Gynecology and Obstetrics (FIGO) 2009 classification. The patients had previously undergone radical surgery. Correlation of the SCC-Ag level with clinicopathological features and the predictive value of SCC-Ag for LNM were analyzed.High preoperative SCC-Ag level was correlated with FIGO stage (P = .001), tumor diameter >4 cm (P
ISSN:	0025-7974 1536-5964
DOI:	10.1097/MD.0000000000026960