Postpartum atypical hemolytic uremic syndrome: Evaluating thrombotic microangiopathy in the pregnant woman

Acute kidney injury in women during pregnancy and the puerperium is often ascribed to hypertensive complications of pregnancy, especially pre-eclampsia. However, rarer causes, including atypical hemolytic uremic syndrome (aHUS) can be triggered by pregnancy. We present a case of a woman with post-pa...

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Veröffentlicht in:Obstetric medicine 2021-06, Vol.14 (2), p.105-108
Hauptverfasser: So, S, Fischer, E, Gangadharan Komala, M, Bose, B
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creator So, S
Fischer, E
Gangadharan Komala, M
Bose, B
description Acute kidney injury in women during pregnancy and the puerperium is often ascribed to hypertensive complications of pregnancy, especially pre-eclampsia. However, rarer causes, including atypical hemolytic uremic syndrome (aHUS) can be triggered by pregnancy. We present a case of a woman with post-partum acute kidney injury due to aHUS, which was successfully treated with the C5a inhibitor eculizumab. We also present a summary of the evaluation and management of thrombotic microangiopathy in pregnancy.
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subjects Case Reports
Injuries
Kidneys
Monoclonal antibodies
Preeclampsia
Pregnancy
Pregnancy complications
Vein & artery diseases
Womens health
title Postpartum atypical hemolytic uremic syndrome: Evaluating thrombotic microangiopathy in the pregnant woman
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