Utility of a safety switch to abrogate CD19.CAR T-cell–associated neurotoxicity

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Bibliographische Detailangaben
Veröffentlicht in:	Blood 2021-06, Vol.137 (23), p.3306-3309
Hauptverfasser:	Foster, Matthew C., Savoldo, Barbara, Lau, Winnie, Rubinos, Clio, Grover, Natalie, Armistead, Paul, Coghill, James, Hagan, Robert S., Morrison, Kaitlin, Buchanan, Faith Brianne, Cheng, Catherine, Laing, Spencer, Ivanova, Anastasia, West, John, Foster, Aaron, Serody, Jonathan, Dotti, Gianpietro
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antigens, CD19 - immunology B-ALL CD19 CAR T cells Clinical Trials and Observations Humans ICANS Immunobiology and Immunotherapy IMMUNOBIOLOGY, Cytotoxic T cells Immunotherapy, Adoptive - adverse effects inducible Caspase 9 Letter to Blood NEOPLASIA, Lymphoid Leukemias: Immunotherapeutic approaches Neoplasm Proteins - immunology Neurotoxicity Syndromes - etiology Neurotoxicity Syndromes - immunology Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - immunology Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - therapy safety switch
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